BDBM50139256 CHEMBL158595::N-[(R)-2-(4-{3-[4-(5-Cyclopentylmethyl-[1,2,4]oxadiazol-3-yl)-3-fluoro-phenoxy]-propyl}-piperazin-1-yl)-1-methyl-2-oxo-ethyl]-2-(4-dimethylamino-phenyl)-acetamide

SMILES C[C@@H](NC(=O)c1ccc(cc1)N(C)C)C(=O)N1CCN(CCCOc2ccc(-c3noc(CC4CCCC4)n3)c(F)c2)CC1

InChI Key InChIKey=LSLKPVQOFVGVSL-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50139256   

TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139256(N-[(R)-2-(4-{3-[4-(5-Cyclopentylmethyl-[1,2,4]oxad...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity for rat histamine H3 receptor on rat cortical cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139256(N-[(R)-2-(4-{3-[4-(5-Cyclopentylmethyl-[1,2,4]oxad...)
Affinity DataKi:  15nMAssay Description:Binding affinity for human histamine H3 receptor on human colon cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139256(N-[(R)-2-(4-{3-[4-(5-Cyclopentylmethyl-[1,2,4]oxad...)
Affinity DataKi:  890nMAssay Description:Binding affinity towards histamine H1 receptor of human colon cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139256(N-[(R)-2-(4-{3-[4-(5-Cyclopentylmethyl-[1,2,4]oxad...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards histamine H4 receptor of human colon cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139256(N-[(R)-2-(4-{3-[4-(5-Cyclopentylmethyl-[1,2,4]oxad...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards histamine H2 receptor of human colon cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed