BDBM50139352 CHEMBL161203::[2-(4-tert-Butyl-thiazol-2-ylsulfanyl)-ethyl]-dimethyl-amine

SMILES CN(C)CCSc1nc(cs1)C(C)(C)C

InChI Key InChIKey=OSPHUVJGYFZGRF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139352   

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139352(CHEMBL161203 | [2-(4-tert-Butyl-thiazol-2-ylsulfan...)
Affinity DataKi:  22nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139352(CHEMBL161203 | [2-(4-tert-Butyl-thiazol-2-ylsulfan...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity towards human dopamine receptor D2 by the displacement of [3H]-Spiperone radioligand from the cloned receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139352(CHEMBL161203 | [2-(4-tert-Butyl-thiazol-2-ylsulfan...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]-Ketanserin radioligand from the cloned receptor expressed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139352(CHEMBL161203 | [2-(4-tert-Butyl-thiazol-2-ylsulfan...)
Affinity DataKi:  2.20E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed