BDBM50139374 (6-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-pyridin-3-yl)-morpholin-4-yl-methanone::CHEMBL159087

SMILES C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cn1)C(=O)N1CCOCC1

InChI Key InChIKey=STRFUFNUDIMYMO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139374   

TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139374((6-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-ben...)
Affinity DataKi:  0.550nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139374((6-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-ben...)
Affinity DataKi:  0.550nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139374((6-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-ben...)
Affinity DataKi:  1.60nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139374((6-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-ben...)
Affinity DataKi:  1.60nMAssay Description:Binding potency by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed