BDBM50139380 4-{2-[2-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-benzonitrile::CHEMBL160113

SMILES OC[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N

InChI Key InChIKey=JFCPJZQAWZEYPU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139380   

TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139380(4-{2-[2-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-ethy...)
Affinity DataKi:  2.20nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139380(4-{2-[2-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-ethy...)
Affinity DataKi:  2.20nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139380(4-{2-[2-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-ethy...)
Affinity DataKi:  26nMAssay Description:Binding potency by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139380(4-{2-[2-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-ethy...)
Affinity DataKi:  26nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed