BDBM50139398 (4-{2-[2-(3,6-Dihydro-2H-pyridin-1-yl)-ethyl]-benzofuran-5-yl}-phenyl)-morpholin-4-yl-methanone::CHEMBL161101

SMILES O=C(N1CCOCC1)c1ccc(cc1)-c1ccc2oc(CCN3CCC=CC3)cc2c1

InChI Key InChIKey=LPLQDVMVHQTAGL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139398   

TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139398((4-{2-[2-(3,6-Dihydro-2H-pyridin-1-yl)-ethyl]-benz...)
Affinity DataKi:  5.90nMAssay Description:Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139398((4-{2-[2-(3,6-Dihydro-2H-pyridin-1-yl)-ethyl]-benz...)
Affinity DataKi:  5.90nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139398((4-{2-[2-(3,6-Dihydro-2H-pyridin-1-yl)-ethyl]-benz...)
Affinity DataKi:  17nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139398((4-{2-[2-(3,6-Dihydro-2H-pyridin-1-yl)-ethyl]-benz...)
Affinity DataKi:  17nMAssay Description:Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed