BDBM50139621 4-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-phenoxy}-pyridine-2-carboxylic acid methylamide::CHEMBL353584

SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cc(on3)C(C)(C)C)cc2)ccn1

InChI Key InChIKey=ZZBDEZLIENWAAA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139621   

TargetVascular endothelial growth factor receptor 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50139621(4-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)
Affinity DataIC50: 17nMAssay Description:Inhibition of VEGFR2 (unknown origin) by [33P]radiolabeled methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139621(4-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed