BDBM50139640 CHEMBL165272::N-4-Substituted-benzyl-N'-tert-butylbenzyl thiourea derivative::N-benzyl-4-sulfamide-N'-(4-tert-butylbenzyl)thiourea

SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(N)(=O)=O)cc2)cc1

InChI Key InChIKey=NWVSMWBHUXOVRR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139640   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50139640(N-4-Substituted-benzyl-N'-tert-butylbenzyl thioure...)
Affinity DataKi:  650nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50139640(N-4-Substituted-benzyl-N'-tert-butylbenzyl thioure...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro antagonist activity at the vanilloid receptor in rat DRG neurons.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2018
Entry Details Article
PubMed