BDBM50139837 CHEMBL3764598

SMILES COCCOc1ccc(cc1)N1CCN(CC1)C(=O)c1cnc2c(CNC(=O)c3nc(N)nc4c(F)cccc34)cccc2c1

InChI Key InChIKey=XPGISRLOZOMIJJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50139837   

TargetAdenosine receptor A2a(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139837(CHEMBL3764598)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]SCH-58261 from human adenosine A2A receptor expressed in HEK cell membranes after 60 mins by microplate scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2017
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139837(CHEMBL3764598)
Affinity DataKi:  11nMAssay Description:Binding affinity to rat A2A adenosine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2017
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139837(CHEMBL3764598)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes after 60 mins by microplate scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2017
Entry Details Article
PubMed