BDBM50139864 CHEMBL3765402::US10577361, E36

SMILES Cc1ncoc1-c1nnc(SCCCN2CCOC(C2)c2ccc(C)cc2)n1C

InChI Key InChIKey=HOXIFZKRDKLRKX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50139864   

TargetD(3) dopamine receptor(Rat)
Aptuit

Curated by ChEMBL
LigandPNGBDBM50139864(CHEMBL3765402 | US10577361, E36)
Affinity DataKi:  501nMAssay Description:Displacement of [125I]-7-OH-PIPAT from rat brain dopamine D3 receptor after 45 mins by microplate scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2017
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Indivior

US Patent
LigandPNGBDBM50139864(CHEMBL3765402 | US10577361, E36)
Affinity DataKi:  676nMAssay Description:[3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
Indivior

US Patent
LigandPNGBDBM50139864(CHEMBL3765402 | US10577361, E36)
Affinity DataKi: <1.00E+4nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO cells after 90 mins by [35S]-GTPgamma S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2017
Entry Details Article
PubMed