BDBM50140251 CHEMBL3759614

SMILES Cc1ccc(cc1)-c1ncc(OCC2CCNCC2)cc1-c1ccc(CO)cc1

InChI Key InChIKey=XMDKHHYDZUATHI-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140251   

TargetLysine-specific histone demethylase 1A(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50140251(CHEMBL3759614)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) using dimethylated H3K4 peptide substrate preincubated for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50140251(CHEMBL3759614)
Affinity DataIC50: 6.26E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed