BDBM50140516 CHEMBL23110::N-{4-[(S)-1-Amino-2-(3,3-difluoro-pyrrolidin-1-yl)-2-oxo-ethyl]-cyclohexyl}-3,4-difluoro-benzamide

SMILES N[C@@H]([C@H]1CC[C@@H](CC1)NC(=O)c1ccc(F)c(F)c1)C(=O)N1CCC(F)(F)C1

InChI Key InChIKey=SCVRXRIXRGTJCH-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50140516   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140516(N-{4-[(S)-1-Amino-2-(3,3-difluoro-pyrrolidin-1-yl)...)
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against human Dipeptidylpeptidase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140516(N-{4-[(S)-1-Amino-2-(3,3-difluoro-pyrrolidin-1-yl)...)
Affinity DataIC50: 660nMAssay Description:Inhibitory activity against human quiescent cell proline dipeptidase (QPP) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140516(N-{4-[(S)-1-Amino-2-(3,3-difluoro-pyrrolidin-1-yl)...)
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity towards human ERG potassium ion channel was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed