BDBM50140524 CHEMBL23924::N-{4-[(S)-1-Amino-2-((R)-3-fluoro-pyrrolidin-1-yl)-2-oxo-ethyl]-cyclohexyl}-3,4-difluoro-benzamide

SMILES N[C@@H]([C@H]1CC[C@@H](CC1)NC(=O)c1ccc(F)c(F)c1)C(=O)N1CC[C@@H](F)C1

InChI Key InChIKey=UUCMWQOGZNNWGQ-GDLHICMESA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50140524   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140524(CHEMBL23924 | N-{4-[(S)-1-Amino-2-((R)-3-fluoro-py...)
Affinity DataKi:  7.30E+4nMAssay Description:Binding affinity of the compound towards human ERG potassium ion channel was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140524(CHEMBL23924 | N-{4-[(S)-1-Amino-2-((R)-3-fluoro-py...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against human Dipeptidyl-peptidase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140524(CHEMBL23924 | N-{4-[(S)-1-Amino-2-((R)-3-fluoro-py...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory activity against human quiescent cell proline dipeptidase (QPP) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed