BDBM50140534 CHEMBL431885::N-{4-[(S)-1-Amino-2-((3S,4S)-3,4-difluoro-pyrrolidin-1-yl)-2-oxo-ethyl]-cyclohexyl}-4-trifluoromethoxy-benzenesulfonamide

SMILES N[C@@H]([C@H]1CC[C@@H](CC1)NS(=O)(=O)c1ccc(OC(F)(F)F)cc1)C(=O)N1C[C@H](F)[C@@H](F)C1

InChI Key InChIKey=GDDMQXKXVHMJDK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140534   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140534(N-{4-[(S)-1-Amino-2-((3S,4S)-3,4-difluoro-pyrrolid...)
Affinity DataIC50: 870nMAssay Description:Inhibitory activity against human Dipeptidylpeptidase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140534(N-{4-[(S)-1-Amino-2-((3S,4S)-3,4-difluoro-pyrrolid...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibitory activity against human quiescent cell proline dipeptidase (QPP) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed