BDBM50140539 (S)-2-Amino-2-cyclohexyl-1-((R)-3-fluoro-pyrrolidin-1-yl)-ethanone::CHEMBL23981

SMILES N[C@@H](C1CCCCC1)C(=O)N1CC[C@@H](F)C1

InChI Key InChIKey=MSOYZLRUNBBCGC-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50140539   

TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50140539((S)-2-Amino-2-cyclohexyl-1-((R)-3-fluoro-pyrrolidi...)
Affinity DataKi:  128nMAssay Description:Inhibitory constant against Dipeptidylpeptidase IV activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50140539((S)-2-Amino-2-cyclohexyl-1-((R)-3-fluoro-pyrrolidi...)
Affinity DataIC50: 340nMAssay Description:Inhibitory activity against human Dipeptidylpeptidase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140539((S)-2-Amino-2-cyclohexyl-1-((R)-3-fluoro-pyrrolidi...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibitory activity against human quiescent cell proline dipeptidase (QPP) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140539((S)-2-Amino-2-cyclohexyl-1-((R)-3-fluoro-pyrrolidi...)
Affinity DataKi: >9.00E+4nMAssay Description:Binding affinity towards human ERG potassium ion channel was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed