BDBM50140541 (S)-2-Amino-2-cyclohexyl-1-(3,3-difluoro-pyrrolidin-1-yl)-ethanone::(S)-2-amino-2-cyclohexyl-1-(3,3-difluoropyrrolidin-1-yl)ethanone::CHEMBL280658

SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC(F)(F)C1

InChI Key InChIKey=ICOHSUPELKBBLT-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50140541   

TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50140541((S)-2-Amino-2-cyclohexyl-1-(3,3-difluoro-pyrrolidi...)
Affinity DataKi:  28nMAssay Description:Inhibitory constant against Dipeptidylpeptidase IV activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50140541((S)-2-Amino-2-cyclohexyl-1-(3,3-difluoro-pyrrolidi...)
Affinity DataIC50: 73nMAssay Description:Inhibitory activity against human Dipeptidylpeptidase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50140541((S)-2-Amino-2-cyclohexyl-1-(3,3-difluoro-pyrrolidi...)
Affinity DataIC50: 73nMAssay Description:Inhibition of human DPP4 expressed in baculovirus systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140541((S)-2-Amino-2-cyclohexyl-1-(3,3-difluoro-pyrrolidi...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against human quiescent cell proline dipeptidase (QPP) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140541((S)-2-Amino-2-cyclohexyl-1-(3,3-difluoro-pyrrolidi...)
Affinity DataKi: >9.00E+4nMAssay Description:Binding affinity towards human ERG potassium ion channel was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed