BDBM50140707 5-(3-chloro-4-methylphenyl)-3-phenyl-(3R,3aS,6aR)-spiro[perhydrofuro[3,4-c]pyrrole-1,2''-(2'',3''-dihydro-1''H-indene)]-1'',3'',4,6-tetraone::CHEMBL26946::CHEMBL281883

SMILES Cc1ccc(cc1Cl)-n1c(O)c2C(OC3(C(=O)c4ccccc4C3=O)c2c1O)c1ccccc1

InChI Key InChIKey=WZLJTSSHRBYEDZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50140707   

TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140707(CHEMBL26946 | 5-(3-chloro-4-methylphenyl)-3-phenyl...)
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140707(CHEMBL26946 | 5-(3-chloro-4-methylphenyl)-3-phenyl...)
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140707(CHEMBL26946 | 5-(3-chloro-4-methylphenyl)-3-phenyl...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140707(CHEMBL26946 | 5-(3-chloro-4-methylphenyl)-3-phenyl...)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140707(CHEMBL26946 | 5-(3-chloro-4-methylphenyl)-3-phenyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140707(CHEMBL26946 | 5-(3-chloro-4-methylphenyl)-3-phenyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed