BDBM50140726 13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-phenyl-(1S,12R,13S,14R)-10,15-dioxatetracyclo[7.6.0.01,12.03,8]pentadeca-3(8),4,6-triene-13-carboxamide::CHEMBL25737

SMILES OC1c2ccccc2C2OC(=O)[C@@H]3[C@@H]([C@@H](O[C@@]123)c1ccccc1)C(=O)Nc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=SJCQIKMJLOJSKF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50140726   

TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140726(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)
Affinity DataIC50: 4.90E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140726(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)
Affinity DataIC50: 4.90E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140726(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)
Affinity DataIC50: 1.40E+4nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140726(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed