BDBM50141079 6-[4-(1-Aza-bicyclo[2.2.2]oct-2-ylmethoxy)-naphthalen-1-yl]-pyridin-2-ylamine::CHEMBL39186

SMILES Nc1cccc(n1)-c1ccc(OCC2CC3CCN2CC3)c2ccccc12

InChI Key InChIKey=LVAYROCXCGELAH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50141079   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141079(6-[4-(1-Aza-bicyclo[2.2.2]oct-2-ylmethoxy)-naphtha...)
Affinity DataIC50:  96.3nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141079(6-[4-(1-Aza-bicyclo[2.2.2]oct-2-ylmethoxy)-naphtha...)
Affinity DataIC50:  88nMAssay Description:In vitro inhibition of rat neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141079(6-[4-(1-Aza-bicyclo[2.2.2]oct-2-ylmethoxy)-naphtha...)
Affinity DataIC50:  3.77E+3nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141079(6-[4-(1-Aza-bicyclo[2.2.2]oct-2-ylmethoxy)-naphtha...)
Affinity DataIC50:  5.80E+3nMAssay Description:In vitro inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed