BDBM50141581 4-(3-Chloro-4-methoxy-benzylamino)-7-trifluoromethyl-quinoline-3-carboxylic acid ethyl ester::CHEMBL41950
SMILES CCOC(=O)c1cnc2cc(ccc2c1NCc1ccc(OC)c(Cl)c1)C(F)(F)F
InChI Key InChIKey=XXAGNOMNFKSMBE-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50141581
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity of compound against phosphodiesterase 3 was testedMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphodiesterase 2More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B(Bovine)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphodiesterase 1 of bovine heartMore data for this Ligand-Target Pair
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of phosphodiesterase 6More data for this Ligand-Target Pair