BDBM50142135 2-[4-({[2-(Acetimidoyl-methyl-amino)-ethyl]-methyl-amino}-methyl)-benzoylamino]-5-chloro-N-(5-chloro-pyridin-2-yl)-benzamide::CHEMBL174791

SMILES CN(CCN(C)C(C)=N)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1

InChI Key InChIKey=NOISQJMTOKEJSD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50142135   

TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142135(2-[4-({[2-(Acetimidoyl-methyl-amino)-ethyl]-methyl...)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142135(2-[4-({[2-(Acetimidoyl-methyl-amino)-ethyl]-methyl...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against activated protein CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142135(2-[4-({[2-(Acetimidoyl-methyl-amino)-ethyl]-methyl...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against tissue type plasminogen activator.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142135(2-[4-({[2-(Acetimidoyl-methyl-amino)-ethyl]-methyl...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142135(2-[4-({[2-(Acetimidoyl-methyl-amino)-ethyl]-methyl...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142135(2-[4-({[2-(Acetimidoyl-methyl-amino)-ethyl]-methyl...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed