BDBM50142346 CHEMBL41078::N-[4-(5-Chloro-2-hydroxy-benzyl)-2-oxo-6-trifluoromethyl-1,2-dihydro-quinolin-3-yl]-C,C,C-trifluoro-methanesulfonamide

SMILES Oc1ccc(Cl)cc1Cc1c(NS(=O)(=O)C(F)(F)F)c(=O)[nH]c2ccc(cc12)C(F)(F)F

InChI Key InChIKey=IGFJTSGNIPPHTD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142346   

TargetPotassium voltage-gated channel subfamily KQT member 2(Mouse)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50142346(N-[4-(5-Chloro-2-hydroxy-benzyl)-2-oxo-6-trifluoro...)
Affinity DataEC50:  663nMAssay Description:Increased outward current at -40 mV mediated by mouse KCNQ2 channel expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed