BDBM50142879 1-(2-Chloro-2-phenyl-ethyl)-6-methylsulfanyl-4-morpholin-4-yl-1H-pyrazolo[3,4-d]pyrimidine::1-(2-chloro-2-phenylethyl)-6-(methylthio)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidine::4-(1-(2-chloro-2-phenylethyl)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)morpholine::CHEMBL38492

SMILES CSc1nc(N2CCOCC2)c2cnn(CC(Cl)c3ccccc3)c2n1

InChI Key InChIKey=BVHIFJRLYQEDHK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50142879   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50142879(4-(1-(2-chloro-2-phenylethyl)-6-(methylthio)-1H-py...)
Affinity DataKi:  6.31E+3nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50142879(4-(1-(2-chloro-2-phenylethyl)-6-(methylthio)-1H-py...)
Affinity DataKi:  6.50E+3nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50142879(4-(1-(2-chloro-2-phenylethyl)-6-(methylthio)-1H-py...)
Affinity DataKi:  6.50E+3nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed