BDBM50143341 (S)-1-{[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z)-ylidene]-phenyl-methyl}-pyrrolidine-2-carboxylic acid [(S)-1-carbamoyl-2-(4-hydroxy-phenyl)-ethyl]-amide::CHEMBL410312

SMILES NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1\C(=C1/N=C(OC1=O)c1ccc(Cl)cc1Cl)c1ccccc1

InChI Key InChIKey=HKFTVJKPJYNBRB-AFRYVWSKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50143341   

TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50143341((S)-1-{[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50143341((S)-1-{[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z)-...)
Affinity DataIC50:  430nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50143341((S)-1-{[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z)-...)
Affinity DataIC50:  2.74E+4nMAssay Description:Inhibition of Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed