BDBM50143844 3-{[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza-spiro[4.5]decane-8-carbonyl]-amino}-2-(toluene-4-sulfonylamino)-propionic acid::CHEMBL66367

SMILES Cc1ccc(cc1)S(=O)(=O)N[C@@H](CNC(=O)N1CCC2(CCN(C2=O)c2ccc(cc2)C(N)=N)CC1)C(O)=O

InChI Key InChIKey=FAUWCTMBSRSLQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143844   

TargetIntegrin alpha-IIb/beta-3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143844(3-{[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza-spi...)
Affinity DataIC50: 1nMAssay Description:Tested for inhibition of the binding of fibrinogen to purified human GPIIb-IIIa in a 96-well format (ELISA assay)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143844(3-{[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza-spi...)
Affinity DataIC50: 66nMAssay Description:Inhibition of platelet aggregation induced by 20 uM adenosine 5-diphosphate (ADP) in citreated human platelet rich plasma (h-PRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed