BDBM50143848 5-[3-(4-Carbamimidoyl-phenyl)-1-methyl-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-yl]-5-oxo-pentanoic acid::CHEMBL292126

SMILES CN1C(=O)N(C(=O)C11CCN(CC1)C(=O)CCCC(O)=O)c1ccc(cc1)C(N)=N

InChI Key InChIKey=VDXLJYFKMUKNFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143848   

TargetIntegrin alpha-IIb/beta-3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143848(5-[3-(4-Carbamimidoyl-phenyl)-1-methyl-2,4-dioxo-1...)
Affinity DataIC50: 100nMAssay Description:Tested for inhibition of the binding of fibrinogen to purified human GPIIb-IIIa in a 96-well format (ELISA assay)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143848(5-[3-(4-Carbamimidoyl-phenyl)-1-methyl-2,4-dioxo-1...)
Affinity DataIC50: 700nMAssay Description:Inhibition of platelet aggregation induced by 20 uM adenosine 5-diphosphate (ADP) in citreated human platelet rich plasma (h-PRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed