BDBM50143851 5-[3-(4-Carbamimidoyl-phenyl)-1-methyl-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-yl]-2-(3,5-dimethyl-isoxazole-4-sulfonylamino)-5-oxo-pentanoic acid::CHEMBL62813

SMILES CN1C(=O)N(C(=O)C11CCN(CC1)C(=O)CC[C@H](NS(=O)(=O)c1c(C)noc1C)C(O)=O)c1ccc(cc1)C(N)=N

InChI Key InChIKey=ZQUWZIRXWNVFRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143851   

TargetIntegrin alpha-IIb/beta-3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143851(5-[3-(4-Carbamimidoyl-phenyl)-1-methyl-2,4-dioxo-1...)
Affinity DataIC50: 16nMAssay Description:Tested for inhibition of the binding of fibrinogen to purified human GPIIb-IIIa in a 96-well format (ELISA assay)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143851(5-[3-(4-Carbamimidoyl-phenyl)-1-methyl-2,4-dioxo-1...)
Affinity DataIC50: 118nMAssay Description:Inhibition of platelet aggregation induced by 20 uM adenosine 5-diphosphate (ADP) in citreated human platelet rich plasma (h-PRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed