BDBM50144475 CHEMBL70574::N-{3-[Benzyl-(4-methyl-benzyl)-amino]-2-methyl-phenyl}-methanesulfonamide

SMILES Cc1ccc(CN(Cc2ccccc2)c2cccc(NS(C)(=O)=O)c2C)cc1

InChI Key InChIKey=VESWLSZJWPMIJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144475   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144475(N-{3-[Benzyl-(4-methyl-benzyl)-amino]-2-methyl-phe...)
Affinity DataIC50: 58nMAssay Description:Binding affinity against human Glucocorticoid receptor (GR) using [3H]dexamethasone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144475(N-{3-[Benzyl-(4-methyl-benzyl)-amino]-2-methyl-phe...)
Affinity DataIC50: 1.10E+3nMAssay Description:Functional activity towards human Glucocorticoid receptor in genetically engineered cell line containing glucocorticoid response element and reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed