BDBM50144668 2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl)-3-[3-(3-fluoro-4-methanesulfonylamino-benzyl)-thioureido-N-hydroxy]-propyl ester::CHEMBL75043

SMILES CC(C)(C)C(=O)OCC(CN(O)C(=S)NCc1ccc(NS(C)(=O)=O)c(F)c1)Cc1ccc(cc1)C(C)(C)C

InChI Key InChIKey=YBPJABXYZLIILW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144668   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50144668(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)
Affinity DataKi:  405nMAssay Description:Binding affinity towards rat vanilloid receptor subtype 1 expressed in CHO cells by [3H]RTX displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50144668(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)
Affinity DataIC50: 1.01E+4nMAssay Description:In vitro antagonist effect against 50 nM capsaicin-induced 45 [Ca2+] influx in vanilloid receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed