BDBM50145078 2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-benzoimidazole::CHEMBL309372

SMILES COc1ccccc1N1CCN(Cc2nc3ccccc3[nH]2)CC1

InChI Key InChIKey=GRGYFXDAOZBGPF-UHFFFAOYSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50145078   

TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145078(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50145078(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human D2R expressed in HEK293 cells incubated for 3 mins by FLIPR analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145078(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Affinity DataEC50:  12.4nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145078(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Affinity DataEC50:  5.60nMAssay Description:Effective concentration against human Dopamine receptor D4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed