BDBM50145230 5-Butyl-2-phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine::CHEMBL340657

SMILES CCCCc1nc2n[nH]cc2c2nc(nn12)-c1ccccc1

InChI Key InChIKey=AYOYRISPVKKGIT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50145230   

TargetAdenosine receptor A2b(Homo sapiens (Human))
Otsuka Pharmaceutical Factory

Curated by ChEMBL
LigandPNGBDBM50145230(5-Butyl-2-phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo...)
Affinity DataIC50: >2.60E+3nMAssay Description:Displacement of specific [3H]-DPCPX binding at human adenosine A2B receptor expressed in HEK-293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Otsuka Pharmaceutical Factory

Curated by ChEMBL
LigandPNGBDBM50145230(5-Butyl-2-phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo...)
Affinity DataIC50: >190nMAssay Description:Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Otsuka Pharmaceutical Factory

Curated by ChEMBL
LigandPNGBDBM50145230(5-Butyl-2-phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo...)
Affinity DataIC50:  190nMAssay Description:Binding affinity for human adenosine A2A receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Otsuka Pharmaceutical Factory

Curated by ChEMBL
LigandPNGBDBM50145230(5-Butyl-2-phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo...)
Affinity DataIC50:  2.10nMAssay Description:Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Otsuka Pharmaceutical Factory

Curated by ChEMBL
LigandPNGBDBM50145230(5-Butyl-2-phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo...)
Affinity DataIC50:  2.10nMAssay Description:Binding affinity for human adenosine A3 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Otsuka Pharmaceutical Factory

Curated by ChEMBL
LigandPNGBDBM50145230(5-Butyl-2-phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo...)
Affinity DataIC50: >27nMAssay Description:Displacement of specific [3H]-DPCPX binding at human adenosine A1 receptor expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed