BDBM50145490 (2S,3R)-3-(4-Hydroxy-benzyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol::CHEMBL313941

SMILES Oc1ccc(C[C@H]2Sc3cc(O)ccc3O[C@H]2c2ccc(OCCN3CCCCC3)cc2)cc1

InChI Key InChIKey=DUNNSQNKGZRPRD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50145490   

TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145490((2S,3R)-3-(4-Hydroxy-benzyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50: 2.70nMAssay Description:Binding affinity towards human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145490((2S,3R)-3-(4-Hydroxy-benzyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50: 14nMAssay Description:In vivo inhibition of human ERalpha/ERbeta co-expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145490((2S,3R)-3-(4-Hydroxy-benzyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50: 308nMAssay Description:Binding affinity towards human estrogen receptor beta (ERbeta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed