BDBM50145770 6-Amino-2-[(S)-2-((S)-2-{(S)-2-[((R)-{1-[(S)-2-((S)-2-amino-propionylamino)-5-guanidino-1-oxo-pentyl]-pyrrolidin-2-yl}-oxo-methyl)-amino]-1-oxo-3-phenyl-propylamino}-1-oxo-propylamino)-4-carbamoyl-1-oxo-butylamino]-hexanoic acid::CHEMBL310987

SMILES C[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(O)=O

InChI Key InChIKey=CGCXTKPVWBLRRX-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50145770   

TargetE3 ubiquitin-protein ligase XIAP(Human)
University of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandPNGBDBM50145770(6-Amino-2-[(S)-2-((S)-2-{(S)-2-[((R)-{1-[(S)-2-((S...)
Affinity DataKd:  20nMAssay Description:Dissociation constant for XIAP BIR3 protein using different binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
University of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandPNGBDBM50145770(6-Amino-2-[(S)-2-((S)-2-{(S)-2-[((R)-{1-[(S)-2-((S...)
Affinity DataKd:  38nMAssay Description:Dissociation constant for XIAP BIR3 protein in FP-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
University of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandPNGBDBM50145770(6-Amino-2-[(S)-2-((S)-2-{(S)-2-[((R)-{1-[(S)-2-((S...)
Affinity DataIC50: 570nMAssay Description:Inhibitory concentration of compound against XIAP BIR3 proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed