BDBM50145796 6-(4-Phenylsulfanyl-phenylsulfanylmethyl)-pteridine-2,4-diamine::CHEMBL83553

SMILES Nc1nc(N)c2nc(CSc3ccc(Sc4ccccc4)cc3)cnc2n1

InChI Key InChIKey=LMHGBFYJFBCPAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145796   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50145796(6-(4-Phenylsulfanyl-phenylsulfanylmethyl)-pteridin...)
Affinity DataIC50: 770nMAssay Description:Concentration required to inhibit the Toxoplasma gondii Dihydrofolate reductase by 50% was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50145796(6-(4-Phenylsulfanyl-phenylsulfanylmethyl)-pteridin...)
Affinity DataIC50: 2.50E+5nMAssay Description:Concentration required to inhibit the rat liver Dihydrofolate reductase by 50% was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed