BDBM50145925 CHEMBL3764475

SMILES c1c(ncnc1N)C(F)(F)F

InChI Key InChIKey=FIAIKJQZLXLGCR-UHFFFAOYSA-N

Data  1 IC50  2 Kd

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50145925   

TargetCholine kinase alpha(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145925(CHEMBL3764475)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetCholine kinase alpha(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145925(CHEMBL3764475)
Affinity DataKd:  6.30E+5nMAssay Description:Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145925(CHEMBL3764475)
Affinity DataKd:  6.70E+5nMAssay Description:Binding affinity to carbonic anhydrase2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed