BDBM50146257 (2S,3R)-2-[4-(2-Dimethylamino-ethoxy)-phenyl]-3-(3-hydroxy-phenyl)-2,3-dihydro-benzo[1,4]oxathiin-6-ol::CHEMBL329902

SMILES CN(C)CCOc1ccc(cc1)[C@@H]1Oc2ccc(O)cc2S[C@@H]1c1cccc(O)c1

InChI Key InChIKey=LZVVYZMWHNBABR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146257   

TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146257((2S,3R)-2-[4-(2-Dimethylamino-ethoxy)-phenyl]-3-(3...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]17-beta-estradiol from full length human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146257((2S,3R)-2-[4-(2-Dimethylamino-ethoxy)-phenyl]-3-(3...)
Affinity DataIC50: 2.30nMAssay Description:Potency in cellular transactivation assay utilizing HEK293 cells stably co-transfected with human estrogen receptor alpha and the alkaline phosphatas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146257((2S,3R)-2-[4-(2-Dimethylamino-ethoxy)-phenyl]-3-(3...)
Affinity DataIC50: 7.30nMAssay Description:Potency in cellular transactivation assay utilizing HEK293 cells stably co-transfected with human estrogen receptor beta and the alkaline phosphatase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146257((2S,3R)-2-[4-(2-Dimethylamino-ethoxy)-phenyl]-3-(3...)
Affinity DataIC50: 129nMAssay Description:Displacement of [3H]17-beta-estradiol from full length human estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed