BDBM50146354 2-{4-[(3aR,12bS)-1-(3,3a,8,12b-Tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-piperazin-1-yl}-ethanol::CHEMBL92337

SMILES OCCN1CCN(CC2C[C@H]3[C@H](O2)c2ccccc2Cc2ccccc32)CC1

InChI Key InChIKey=YZIDTWIJPIHTCE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50146354   

TargetHistamine H1 receptor(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146354(2-{4-[(3aR,12bS)-1-(3,3a,8,12b-Tetrahydro-2H-1-oxa...)
Affinity DataKi:  3.70nMAssay Description:Ability to displace [3H]pyrilamine from human cloned histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146354(2-{4-[(3aR,12bS)-1-(3,3a,8,12b-Tetrahydro-2H-1-oxa...)
Affinity DataKi:  87nMAssay Description:Ability to displace [125I]R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146354(2-{4-[(3aR,12bS)-1-(3,3a,8,12b-Tetrahydro-2H-1-oxa...)
Affinity DataKi:  170nMAssay Description:Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed