BDBM50146432 8-(5-Methoxy-[1,2,4]thiadiazol-3-ylmethylsulfanyl)-3-methyl-5-thiazol-2-yl-3,4-dihydro-2H-naphthalen-1-one::CHEMBL98649

SMILES COc1nc(CSc2ccc(-c3nccs3)c3CC(C)CC(=O)c23)ns1

InChI Key InChIKey=XBXOXHQNEMHVJF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146432   

LigandPNGBDBM50146432(8-(5-Methoxy-[1,2,4]thiadiazol-3-ylmethylsulfanyl)...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha-5-beta-3-gamma-2 subunitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50146432(8-(5-Methoxy-[1,2,4]thiadiazol-3-ylmethylsulfanyl)...)
Affinity DataKi:  34nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-2-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50146432(8-(5-Methoxy-[1,2,4]thiadiazol-3-ylmethylsulfanyl)...)
Affinity DataKi:  35nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50146432(8-(5-Methoxy-[1,2,4]thiadiazol-3-ylmethylsulfanyl)...)
Affinity DataKi:  40nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed