BDBM50146436 8-Ethylsulfanyl-3-methyl-5-oxazol-2-yl-3,4-dihydro-2H-naphthalen-1-one::CHEMBL320395

SMILES CCSc1ccc(-c2ncco2)c2CC(C)CC(=O)c12

InChI Key InChIKey=IMNDRTREIHGIIE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146436   

LigandPNGBDBM50146436(8-Ethylsulfanyl-3-methyl-5-oxazol-2-yl-3,4-dihydro...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha-5-beta-3-gamma-2 subunitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50146436(8-Ethylsulfanyl-3-methyl-5-oxazol-2-yl-3,4-dihydro...)
Affinity DataKi:  16nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50146436(8-Ethylsulfanyl-3-methyl-5-oxazol-2-yl-3,4-dihydro...)
Affinity DataKi:  37nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50146436(8-Ethylsulfanyl-3-methyl-5-oxazol-2-yl-3,4-dihydro...)
Affinity DataKi:  38nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-2-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed