BDBM50146440 8-Ethylsulfanyl-3-methyl-5-pyrazin-2-yl-3,4-dihydro-2H-naphthalen-1-one::CHEMBL318370
SMILES CCSc1ccc(-c2cnccn2)c2CC(C)CC(=O)c12
InChI Key InChIKey=LGRQUGHDTPHNOB-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50146440
Affinity DataKi: 2.10nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha-5-beta-3-gamma-2 subunitsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-2-beta-3-gamma-2More data for this Ligand-Target Pair