BDBM50146805 CHEMBL97951::[(cyclohexylmethyl)amino]carbonylphosphonic acid

SMILES OP(O)(=O)C(=O)NCC1CCCCC1

InChI Key InChIKey=XBMRQHZMWARLEG-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50146805   

Target72 kDa type IV collagenase(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146805([(cyclohexylmethyl)amino]carbonylphosphonic acid |...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146805([(cyclohexylmethyl)amino]carbonylphosphonic acid |...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146805([(cyclohexylmethyl)amino]carbonylphosphonic acid |...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-3 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146805([(cyclohexylmethyl)amino]carbonylphosphonic acid |...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-9 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146805([(cyclohexylmethyl)amino]carbonylphosphonic acid |...)
Affinity DataIC50: 7.36E+3nMAssay Description:Inhibition of human Carbonic anhydrase 1-mediated CO2 hydration by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146805([(cyclohexylmethyl)amino]carbonylphosphonic acid |...)
Affinity DataIC50: 7.44E+3nMAssay Description:Inhibition of human Carbonic anhydrase 12-mediated CO2 hydration by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146805([(cyclohexylmethyl)amino]carbonylphosphonic acid |...)
Affinity DataIC50: 8.59E+3nMAssay Description:Inhibition of human Carbonic anhydrase 9-mediated CO2 hydration by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146805([(cyclohexylmethyl)amino]carbonylphosphonic acid |...)
Affinity DataIC50: 9.23E+3nMAssay Description:Inhibition of human Carbonic anhydrase 2-mediated CO2 hydration by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146805([(cyclohexylmethyl)amino]carbonylphosphonic acid |...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-1 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146805([(cyclohexylmethyl)amino]carbonylphosphonic acid |...)
Affinity DataIC50: 8.00E+4nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-8 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed