BDBM50146835 1-(4-Chloro-phenyl)-4-(4-cyclopentyl-piperazin-1-yl)-butane-1,4-dione; hydrochloride::CHEMBL97170
SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCCC1
InChI Key InChIKey=VPARRMQGLNFBBR-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50146835
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to human H3RMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assayMore data for this Ligand-Target Pair