BDBM50147232 3'N-(2-tetrahydro-1H-1-pyrrolylethyl)-1-[4-(5-fluoro-2-methylphenylcarboxamido)benzoyl]spiro[2,3,4,5-tetrahydro-1H-benzo[b]azepine-4,1'-(2'-cyclopentene)]-3'-carboxamide::CHEMBL106938

SMILES Cc1ccc(F)cc1C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCC(=C2)C(=O)NCCN2CCCC2)Cc2ccccc12

InChI Key InChIKey=MVPFSLAMRFZZRY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50147232   

TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50147232(3'N-(2-tetrahydro-1H-1-pyrrolylethyl)-1-[4-(5-fluo...)
Affinity DataIC50: 19nMAssay Description:Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50147232(3'N-(2-tetrahydro-1H-1-pyrrolylethyl)-1-[4-(5-fluo...)
Affinity DataIC50: 29nMAssay Description:Evaluated for intracellular calcium mobilization in HEK293 cells transfected to express human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50147232(3'N-(2-tetrahydro-1H-1-pyrrolylethyl)-1-[4-(5-fluo...)
Affinity DataIC50: 39nMAssay Description:Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50147232(3'N-(2-tetrahydro-1H-1-pyrrolylethyl)-1-[4-(5-fluo...)
Affinity DataIC50: 48nMAssay Description:Evaluated for accumulation of cAMP in transfected HEK293 cells expressing human vasopressin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed