BDBM50147382 4-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-ylsulfanylmethyl]-benzoic acid methyl ester::CHEMBL324619

SMILES COC(=O)c1ccc(CSc2nc3ccccc3n2Cc2ccc(Cl)cc2)cc1

InChI Key InChIKey=DMAAYDZJXUUROB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147382   

TargetD(2) dopamine receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50147382(4-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-ylsulfan...)
Affinity DataKi:  73nMAssay Description:Binding affinity against human recombinant dopamine receptor D2 in presence of 0.5% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50147382(4-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-ylsulfan...)
Affinity DataKi:  297nMAssay Description:Binding affinity against human recombinant dopamine receptor D2 in presence of 0.5% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50147382(4-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-ylsulfan...)
Affinity DataKi:  9.10E+3nMAssay Description:Binding affinity against human recombinant Thromboxane A2 receptor was determined using radioligand competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed