BDBM50147738 1-[1-(1,2,3,4-Tetrahydro-naphthalen-2-yl)-piperidin-4-yl]-1,3-dihydro-indol-2-one::CHEMBL101676

SMILES O=C1Cc2ccccc2N1C1CCN(CC1)C1CCc2ccccc2C1

InChI Key InChIKey=MGIADQYKMHMDKW-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50147738   

TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50147738(1-[1-(1,2,3,4-Tetrahydro-naphthalen-2-yl)-piperidi...)
Affinity DataKi:  29nMAssay Description:Binding affinity against human Nociceptin receptor on CHO cell membranes by [3H]N/OFQ displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50147738(1-[1-(1,2,3,4-Tetrahydro-naphthalen-2-yl)-piperidi...)
Affinity DataKi:  39nMAssay Description:Binding affinity against human Opioid receptor mu 1 on CHO cell membranes was determined by [3H]DAMGO displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50147738(1-[1-(1,2,3,4-Tetrahydro-naphthalen-2-yl)-piperidi...)
Affinity DataKi:  55nMAssay Description:Binding affinity against human Opioid receptor kappa 1 on CHO cell membranes by [3H]U-69593 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50147738(1-[1-(1,2,3,4-Tetrahydro-naphthalen-2-yl)-piperidi...)
Affinity DataEC50:  93nMAssay Description:Concentration required for stimulation of [35S]GTP-gamma-S, binding to human Nociceptin receptor in cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed