BDBM50147789 2-{3-[2,2-Difluoro-2-(1-oxy-pyridin-2-yl)-ethylamino]-2-oxo-2H-pyrazin-1-yl}-N-(2-tetrazol-1-yl-benzyl)-acetamide::CHEMBL441463

SMILES [O-][n+]1ccccc1C(F)(F)CNc1nccn(CC(=O)NCc2ccccc2-n2cnnn2)c1=O

InChI Key InChIKey=NXHSVNNVHFYXIB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50147789   

TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147789(2-{3-[2,2-Difluoro-2-(1-oxy-pyridin-2-yl)-ethylami...)
Affinity DataKi:  1.10nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147789(2-{3-[2,2-Difluoro-2-(1-oxy-pyridin-2-yl)-ethylami...)
Affinity DataKi:  370nMAssay Description:Inhibitory potency of compound against human Coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed