BDBM50148092 7-[3-(2-Chloro-4-phenoxy-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid::CHEMBL111480

SMILES CC1(CCc2ccc(OCCCOc3ccc(Oc4ccccc4)cc3Cl)cc2O1)C(O)=O

InChI Key InChIKey=LNHVXGYUBBGCLW-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148092   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148092(7-[3-(2-Chloro-4-phenoxy-phenoxy)-propoxy]-2-methy...)
Affinity DataIC50:  120nMAssay Description:In vitro binding affinity for human peroxisome proliferator activated receptor alpha using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148092(7-[3-(2-Chloro-4-phenoxy-phenoxy)-propoxy]-2-methy...)
Affinity DataEC50:  360nMAssay Description:In vitro transcriptional activation by human PPAR gamma Gal4 chimeraMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148092(7-[3-(2-Chloro-4-phenoxy-phenoxy)-propoxy]-2-methy...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro binding affinity for human peroxisome proliferator activated receptor gamma using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148092(7-[3-(2-Chloro-4-phenoxy-phenoxy)-propoxy]-2-methy...)
Affinity DataEC50:  80nMAssay Description:In vitro potency of PPAR gene activation against human Peroxisome proliferator activated receptor alpha using chimeric Gal4-hPPAR transactivation ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed