BDBM50148093 2-Methyl-7-[4-(4-phenoxy-2-propyl-phenoxy)-butoxy]-chroman-2-carboxylic acid::CHEMBL110071

SMILES CCCc1cc(Oc2ccccc2)ccc1OCCCCOc1ccc2CCC(C)(Oc2c1)C(O)=O

InChI Key InChIKey=VWFYUDHZTCZXBE-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148093   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148093BDBM50148093(2-Methyl-7-[4-(4-phenoxy-2-propyl-phenoxy)-butoxy]...)
Affinity DataEC50:  3.60E+3nMAssay Description:In vitro potency of PPAR gene activation against human PPAR gamma receptor using chimeric Gal4-hPPAR transactivation assay (TA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148093BDBM50148093(2-Methyl-7-[4-(4-phenoxy-2-propyl-phenoxy)-butoxy]...)
Affinity DataIC50: 5.10E+3nMAssay Description:In vitro binding affinity for human peroxisome proliferator activated receptor gamma using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148093BDBM50148093(2-Methyl-7-[4-(4-phenoxy-2-propyl-phenoxy)-butoxy]...)
Affinity DataEC50:  5.20E+3nMAssay Description:In vitro potency of PPAR gene activation against human Peroxisome proliferator activated receptor alpha using chimeric Gal4-hPPAR transactivation ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148093BDBM50148093(2-Methyl-7-[4-(4-phenoxy-2-propyl-phenoxy)-butoxy]...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro binding affinity for human peroxisome proliferator activated receptor alpha using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed