BDBM50148098 (S)-7-[3-(2-Chloro-4-phenoxy-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid::CHEMBL112790

SMILES C[C@]1(CCc2ccc(OCCCOc3ccc(Oc4ccccc4)cc3Cl)cc2O1)C(O)=O

InChI Key InChIKey=LNHVXGYUBBGCLW-SANMLTNESA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50148098   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148098((S)-7-[3-(2-Chloro-4-phenoxy-phenoxy)-propoxy]-2-m...)
Affinity DataEC50:  4.20E+3nMAssay Description:In vitro potency of PPAR gene activation against human Peroxisome proliferator activated receptor alpha using chimeric Gal4-hPPAR transactivation ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148098((S)-7-[3-(2-Chloro-4-phenoxy-phenoxy)-propoxy]-2-m...)
Affinity DataIC50: >1.50E+4nMAssay Description:In vitro binding affinity for human peroxisome proliferator activated receptor alpha using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148098((S)-7-[3-(2-Chloro-4-phenoxy-phenoxy)-propoxy]-2-m...)
Affinity DataIC50: >1.50E+4nMAssay Description:In vitro binding affinity for human Peroxisome proliferator activated receptor gamma using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148098((S)-7-[3-(2-Chloro-4-phenoxy-phenoxy)-propoxy]-2-m...)
Affinity DataEC50:  7.60E+3nMAssay Description:In vitro potency of PPAR gene activation against human PPAR gamma receptor using chimeric Gal4-hPPAR transactivation assay (TA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148098((S)-7-[3-(2-Chloro-4-phenoxy-phenoxy)-propoxy]-2-m...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro binding affinity for human PPAR gamma receptor using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed