BDBM50148370 5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naphthalen-2-ol::CHEMBL332098

SMILES CNCC[C@H](Oc1cccc2cc(O)ccc12)c1cccs1

InChI Key InChIKey=LEIFDHLVPBJTIV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148370   

TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148370(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  1.06nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporter; Average of two experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148370(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  4.72nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148370(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  163nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporter; Average of two experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed