BDBM50148387 CHEMBL4778550

SMILES CCOC(=O)c1ccc(NC(=O)c2cccc(c2)S(=O)(=O)N2CCCc3ccccc23)s1

InChI Key InChIKey=SPZMRFVNCRFNBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148387   

TargetProtein cereblon/CUL4A/AR(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandPNGBDBM50148387(CHEMBL4778550)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of DHT induced androgen receptor transcription in human LNCaP cells cotransfected with PSA-luc and renilla plasmid incubated for 24 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein cereblon/CUL4A/AR(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandPNGBDBM50148387(CHEMBL4778550)
Affinity DataIC50: 2.03E+3nMAssay Description:Antagonist activity at recombinant androgen receptor (unknown origin) transfected in human LNCaP cells co-transfected with PSA and luciferase incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandPNGBDBM50148387(CHEMBL4778550)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of glucocorticoid receptor transcription in human PC-3 cells cotransfected with MMTV-luc and renilla plasmid at incubated for 24 hrs by Du...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandPNGBDBM50148387(CHEMBL4778550)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at recombinant glucocorticoid receptor (unknown origin) transfected in human PC-3 cells co-transfected with MMTV and luciferase i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed